M值和B值的计算公式
The relationship curve between M-value and Beta-value
M值和B值的对应关系
The histograms of Beta-value (left) and M-value (right) (27578 interrogated CpG sites in total)
M值和B值的分布
minfi包有getM和getBeta来分别计算M-values和Beta-values,包的作者认为,
CHAMP包在load的时候,可以指定计算Beta-value还是M-value
一般来说,具体的β值的意义是:
参考:
https://zhuanlan.zhihu.com/p/108364645
https://link.springer.com/article/10.1186/s41241-017-0041-9